What is antibiotic resistance disease?
The antibiotic-resistant infection is the one, which cannot be curbed in any way with antibiotics. This is increasing day by day and at a swift speed due to the misuse of antibiotics and the misunderstanding of how these antibiotics work and how long they should be taken. It is one of the biggest threats to global health. It can affect any person at any given time and can have fatal consequences. A number of infections like pneumonia, tuberculosis, salmonellosis, etc. are becoming harder and harder to cure since the antibiotics that are needed to treat these infections have become less effective or not effective at all.
Antibiotic-resistant bacteria grow for various reasons through one of the following mechanisms :
- Genetic mutation
- Natural or instinctive resistance of different bacterial types
- A bacteria species getting resistance from a pre-existing one
What can be the solution to this problem?
Antibiotics were produced to save countless lives, which they successfully have over the years. However, in recent years, scientists have found out that there are various antibiotic-resistant infections that are hard to manage and treat. In order to overcome this problem, many doctors give high doses of multiple antibiotics to these patients, which is practically harmful to the lives of these patients. This has led the scientists to discover and investigate newer and potential solutions to this growing problem; CBD is one the recently-investigated compounds to overcome antibiotic resistance and hopefully it can be the solution to this problem in the near future.
How can CBD fight antibiotic-resistant organisms?
Cannabidiol (CBD) has shown effectivity in fighting off infecting microorganisms such as staphylococci and streptococci. In a report conducted in 1976, CBD was studied as well as Tetrahydrocannabinol (THC) and both have shown bactericidal properties, and when they were put in a media containing 4% serum or 5% blood the antibacterial activity is strongly reduced. However, Gram-negative bacteria were shown resistant to both THC and CBD.
CBD target one of the major parts of our brain, the central nervous system (CNS), where the endocannabinoid system (ECS) is targeted through cannabinoid receptors type 1 and 2 (CB1 and CB2). Those receptors are helpful in moderating the CNS and peripheral organs and in regulating their balance. CB1 is mainly associated with regulation of the cognitive activities. CB2 deals with the response of our bodies to inflammation and pain. With the ingestion of these compounds, through the activation of our endocannabinoid system, we will get the best benefits.
CBD was one of the cannabinoid compounds that were investigated and found effective against several strains of Staphylococcus aureus. In vivo, it was found that the effects of cannabinoid compounds exhibited various properties through the activation of cannabinoid receptor type 1 (CB1) such as lowering the incidence of occurring fever and reduction of pro-inflammatory cytokines. On the other hand, activation of CB2 would prevent intestinal damage during sepsis while preventing inflammatory damage as well. Moreover, long term administration of CBD revealed highly significant beneficial effect against the microorganism Staphylococcus pneumonie (Pneumonia-causing germ) where CBD significantly reduced the extent of brain damage.
Killing MRSA with Cannabidiol
Methicillin-Resistant Staphylococcus aureus (MRSA) is one of the common drug-resistant bacteria. MRSA does not give a response to most of the antibiotics. That is why it starts spreading throughout your body. The infection becomes life-threatening for the immunitary system. Researchers have directly applied CBD to this certain bacteria in a lab study. The best fact is that CBD revealed a very high potential for fighting MRSA. They have applied a combination of different cannabinoids. It was found that CBD would be able to destroy MRSA bacteria. The unique natural properties found in CBD will not cause any adverse effect.
Noteworthy, current research in this area remains very limited and the therapeutic potential of CBD in fighting against antibiotic-resistance strains has not been studied in human, even though recent investigations and lab studies have shown promising effects of CBD in regards to treating infections. Therefore, one should be very careful upon taking CBD in any form such as CBD oil and a doctor should be consulted first to choose the right dosage of the product, if it is, at all, possible to treat your infection.