Addiction is the inability to stay away from substances, which give you bliss and happiness once you indulge in it, but are harmful to your body. In spite of consistent harm to yourself, if you are unable to give up on the substance, then you are addicted to it. It is a complicated situation and mostly a brain disorder. The excess dependency on a particular element for your content is what signifies the condition.
What is alcoholism?
Alcoholism is characterized by the excess intake of alcohol that is harmful to your health and can make you sick and intoxicated all the time. This, too, is an addiction in people who find it difficult to abstain from the stupendous intake of the same despite the deterioration in their health. It is the severe form of inability to manage and refrain yourself from the overindulgence. It has various symptoms that can be vigorously harmful to you and your family.
What is CBD?
CBD or Cannabidiol is a compound present in hemp or cannabis plant and has therapeutic health benefits and is extracted for its medical uses. It helps people suffering from anxiety, depression and chronic pain and many other similar diseases. Many countries have started noticing and realizing its benefits and have made it legal while many countries on the globe are yet to do so. Patients, suffering from anxiety disorders and depression, benefit from CBD as it ultimately lowers the tendencies and rinses it out of their system.
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How does CBD help in addiction?
In general, addiction is a chronic disorder which recurs frequently and is characterized by the compulsive need to use drugs and/or other substances with losing the ability to control over-consumption. Cannabidiol (CBD), the second major component of cannabis, is thought to be involved in various neuronal pathways related to drug addiction. A very limited number of preclinical reports suggest that CBD may have therapeutic properties on cocaine, opioid, and psycho-stimulating agents’ addiction. Surprisingly, some preliminary data suggest that it may also be of benefit in overcoming cannabis and tobacco addiction in humans.
Multiple cannabinoid compounds are derived from the marijuana plant and have potential therapeutic effects. However, most of these agents are not thoroughly investigated, despite its widespread legalization in the USA and other countries. Tetrahydrocannabinol (THC) has been well acknowledged to be rewarding and to enhance the sensitivity to other drugs and giving the ‘high’ sensation, cannabidiol (CBD), in contrast, appears to have low reinforcing properties with limited abuse potential and to inhibit drug-seeking behavior. Moreover, CBD’s anxiolytic properties and its minimal side effect support its potential viability as a treatment option for various symptoms associated with drug addiction.
In a randomized recent clinical trial, a total of 24 smokers who wished to stop smoking were given either CBD inhaler or placebo. Individuals on CBD inhaler showed significant reduction in the total number of cigarettes smoked. Surprisingly CBD revealed effectiveness even during the 1st week of treatment. CBD can also exhibit the following functions:
- It can help you increase your concentration level and focus better. It helps you release tension and be a bit relaxed to focus on the good things in life. The constant suicidal thoughts are also curbed when you consume CBD oil.
- It keeps the tendencies of paranoia in check. Addicts are prone to relapses even after thorough medication. CBD helps in this phase.
Noteworthy, further research is still required as current CBD investigations are primarily focused on its effects on opioid drugs, while CBD’s efficacy at various phases of the abuse cycle of other addictive substances remain largely understudied.
Therapeutic potential of CBD in Alcoholism
As CBD has shown effectiveness in managing and treating various addictive behaviors towards a certain number of addictive agents, it has also shown promising effects in managing alcoholism.
In a recent systematic review was conducted in order to determine the credibility of CBD as a candidate therapy for alcohol use disorder. Eight studies used rodent models, 3 used healthy adult volunteers, while 1study used cell culture. In both rodent and cell culture models, CBD revealed a neuroprotective effect against adverse alcohol consequences on the brain. In rodent models, CBD was found to alleviate alcohol-induced liver toxicity. Moreover, CBD attenuates stress-induced alcohol seeking behavior, self-administration, and withdrawal-induced seizures. In human studies, CBD was well tolerated and did not interact with any subjective effect of alcohol. In conclusion, given the beneficial effects on alcohol-related harms and addiction in preclinical models, CBD appears to be promising potential drug in the management of alcohol use disorder. This is further influenced by the absence of abuse liability and well-tolerability of CBD.
Noteworthy, due to the paucity of human investigations, more human preclinical and clinical studies are warranted to know whether these beneficial effects substantively translate into clinically relevant outcomes.